That sounds like it would work but build the box from plexiglass as well and mount draw slides on either side of the box with an actuator on each side that operate off the same switch so they both work at the same time. This idea would work best on an L shaped desk so that you could still put your keyboard on the same type slide system and you would not be confined by size as to how or what direction the mobo, PSU, ODDs, HDDs and card reader or floppy was mounted in the box other than access to the ODD and floppy or card reader set to the front of the box.
what goes around comes around
(RIG)GA-EP45-UD3P, Q9550 @ 3.5 ghz, CM's V8, HD2600XT512mb 128bit, 4gigs OCZ 1066 ddr2, Seagate sata 120 gig & a 320 gig, 2 Liteon sata DVD Burner, My DIY Case, Corsair 550watt PSU, 2ea 19" LCD monitors.